Rapid Communication
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 21, 2006; 12(31): 5037-5043
Published online Aug 21, 2006. doi: 10.3748/wjg.v12.i31.5037
Table 2 Allele and genotype frequencies of the polymorphisms under investigation in CRC patients and healthy controls
AllelesGenotypes
IL-6
CGG allele frequencies (%)P; OR (95% CI)CCCGGGGG genotype frequencies (%)P; OR (95% CI)
CRC14629867.1< 0.0001; 1.77 (1.34-2.34)357611150< 0.0005; 2.10 (1.40-3.16)
Controls18621453.550866432
IL-8
ATT allele frequencies (%)P; OR (95% CI)AAATTTTT genotype frequencies (%)P; OR (95% CI)
CRC18625858.110.467; 1.10401067634.230.256; 0.77
Controls17421854.5(0.84-1.45)42906432(0.49-1.20)
TNFα
GAΑ allele frequencies (%)P; OR (95% CI)GGGAAAΑΑ genotype frequencies (%)P; OR (95% CI)
CRC3608418.920.265; 1.1815256146.310.586; 1.28
Controls3366416(0.83-1.68)14644105(0.53-3.1)
ICAM-1 R241G
GRR allele frequencies (%)P; OR (95% CI)GGGRRRRR genotype frequencies (%)P; OR (95% CI)
CRC3628218.470.002; 1.831447441.80.652; 1.50
Controls3564411(1.23-2.72)1584021(0.26-8.7)
ICAM-1 K469E
EKK allele frequencies (%)P; OR (95% CI)EEEKKKKK genotype frequencies (%)P; OR (95% CI)
CRC23620846.850.031; 1.3570965625.220.221; 1.33
Controls24215839.5(1.03-1.77)77883517.5(0.83-2.12)
PPARγ
CGC allele frequencies (%)P; OR (95% CI)CCCGGGCC genotype frequencies (%)P; OR (95% CI)
CRC3766884.70.001; 1.78164481073.8< 0.001; 2.01
Controls30694 76.5(1.25-2.49)118701259(1.32-3.09)