Usefulness of duodenal biopsy during routine upper gastrointestinal endoscopy for diagnosis of celiac disease

Table 1 Prevalence of celiac disease in 1009 duodenal biopsies performed during upper gastrointestinal endoscopy

	Number	CD n (%)	95% CI
Study population	1009	22 (2.2)	1.4-3.3
Period:
1990-1994	58	2 (3.4)	0.6-13.0
1995-1999	258	8 (3.1)	1.5-6.3
2000-2004	693	12 (1.7)	0.9-3.1
Gender:
Female	600	18 (3)	1.8-4.8
Male	409	4 (1)	0.3-2.7
Age (yr):
14-34	136	3 (2.2)	0.6-6.8
35-54	309	11 (3.6)b	1.9-6.5
55-74	365	7 (1.9)	0.8-4.1
≥ 75	199	1 (0.5)	0.03-3.2
Patient subgroups:
Anemia	514	14 (2.7)	1.6-4.6
Diarrhoea	141	12 (8.5)d	4.7-14.7
Anemia plus diarrhoea	42	8 (19)f	9.1-34.6

^bP < 0.01 (35-54 yr vs≥ 75 yr);

^dP < 0.01 (diarrhea vs anemia);

^fP < 0.0001 (anemia plus diarrhoea vs anemia).