Histopathological comparison of topical therapy modalities for acute radiation proctitis in an experimental rat model

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Aug 14, 2006 (publication date) through Nov 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 14, 2006; 12(30): 4879-4883
Published online Aug 14, 2006. doi: 10.3748/wjg.v12.i30.4879

Table 1 Grading of histological changes on microscopic examination

Structure	Characteristic
Surface epithelium	Loss of cellular height/flattening of cells
	Cellular inflammatory infiltrate
Glands (crypts)	Luminal migration of epithelial nuclei
	Loss of goblet cells
	Mitotic activity
	Cryptitis (migration of segmental neutrophils
	through the crypt wall)
	Eosinophilic crypt abscesses
	Loss of glands
	Atrophy of glands
	Distortion of glands
Lamina propria	Inflammation
	Edema
	Congestion of blood vessels

The abnormalities were assessed as normal (score = 0) or abnormal, ranked according to severity and arranged in quartiles.

Citation: Korkut C, Asoglu O, Aksoy M, Kapran Y, Bilge H, Kiremit-Korkut N, Parlak M. Histopathological comparison of topical therapy modalities for acute radiation proctitis in an experimental rat model. World J Gastroenterol 2006; 12(30): 4879-4883
URL: https://www.wjgnet.com/1007-9327/full/v12/i30/4879.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i30.4879