Topic Highlight
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 14, 2006; 12(30): 4794-4806
Published online Aug 14, 2006. doi: 10.3748/wjg.v12.i30.4794
Table 7 Drugs for the treatment of CD
DrugInfliximab
Dosage5 mg/kg per infusion; usually started at wk 0, 2, and 6 and then repeated every 8 wk if necessary
IndicationsChronically active disease, steroid-refractory and steroid-dependency, maintenance, fistulae
Important side effectsNausea, headache, abdominal pain, infections, sepsis; infusions reactions (early or delayed), reactivation of tuberculosis
MonitoringVital signs around infusion
PregnancyUnknown
CommentsExclude tuberculosis before infusions, consider concommittant use of imunosuppressants (azathioprine) to reduce antibody formation