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Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 14, 2006; 12(30): 4794-4806
Published online Aug 14, 2006. doi: 10.3748/wjg.v12.i30.4794
Table 1 Drugs for the treatment of CD
Drug5-ASA (mesalamine or sulfasalazine)
Dosage3.2-4 g/d
IndicationsMild to moderately active disease, postoperative maintenance
Important side effectsHeadache, nausea and abdominal pain, often during treatment with sulfasalazine (in up to 45% of patients); thrombopenia; interstitial nephitis, pancreatitis;
MonitoringLiver function, full blood count and especially renal function
PregnancySuggested to be safe in conventional doses