Host susceptibility to persistent hepatitis B virus infection

Table 1 Gene polymorphisms associated with clearance of HBV infection

Gene/loci	Population	Sample size	P value	Reference
HLA A 0301	Caucasian	563	0.0005	[30]
HLA -DRB1 1302	Caucasian	563	0.03	[30]
HLA-DRB1 1302	Gambian	638	0.012	[31]
HLA-DRB1 1101/1104	Chinese	190	0.0145	[32]
HLA-DQA1 0301	Chinese	190	0.0167	[32]
HLA-DR13	Korean	1272	< 0.001	[33]
TNF-alpha-238 GG genotype	Chinese	895	0.041	[34]
TNF-alpha-308 A	Korean	1400	< 0.001	[35]
TNF-alpha-857 TT genotype	Chinese	355	0.02	[36]
CTLA-4-1722 C			0.06	[37]
CTLA-4+49 G			0.02	[37]
CCR5 59029 G allele	Chinese	377	0.001	[38]