Effect of genistein on voltage-gated potassium channels in guinea pig proximal colon smooth muscle cells

Figure 1 Two components of voltage-gated potassium currents in guinea pig colon smooth muscle cells and effect of GST. A₁-A₃: Currents recorded every 10 s between -80 and +50 mV then back to -40 mV with holding potential -80 mV in the control (A₁), in the presence of 10 mmol/L TEA (A₂) and TEA and 30 µmol/ GST (A₃). B₁: Currents recorded every 10 s between -80 and +50 mV with holding potential -80 mV in the control; B₂: current in the presence of 5 mmol/L 4-AP developed slowly and showed slower inactivation over 400 ms; B₃: effect of 50 µmol/L GST in the presence of 5 mmol/L 4-AP.