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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 7, 2006; 12(29): 4721-4726
Published online Aug 7, 2006. doi: 10.3748/wjg.v12.i29.4721
Published online Aug 7, 2006. doi: 10.3748/wjg.v12.i29.4721
Table 5 Analysis of published data in chronic HCV patients genotyped for CCR5Δ32 mutation
Authors | Susceptibility | Histological Severity | Response to therapy | Genotype | Patients studied (n) |
Ahlensteil G et al[27,28] | Yes | Not mentioned | Lower ETR1 | Genotype 1 Genotype 2 | 59 3 |
Genotype 3 | 9 | ||||
Genotype 4 | 3 | ||||
Undetermined | 4 | ||||
Glas J et al[29] | No | Not mentioned | No | Genotype 1/4 | 37 |
Genotype 2/3 | 25 | ||||
Goulding C et al[26] | 2Spontaneous viral clearance | 2Lower hepatic inflammation | Not mentioned | Genotype 1b | 283 |
Hellier et al[13] | No | Decreased portal inflammation | No | Stratification not mentioned | |
Konishi et al[30] | No | No | No | Serotype 1 | 53 |
Serotype 2 | 48 | ||||
Serotype 1 + 2 | 4 | ||||
Mascheretti et al[31] | No | No | No | Genotype 1 | 358 |
Genotype 2 | 14 | ||||
Genotype 3 | 79 | ||||
Genotype 4 | 14 | ||||
Promrat et al[12] | No | No | No | Genotype 1 | 243 |
Genotype 2 | 34 | ||||
Genotype 3 | 16 | ||||
Genotype 4 | 3 | ||||
Genotype 5 | 1 | ||||
Undetermined | 42 | ||||
Wald et al[32] | No | Significantly reduced | Not mentioned | Genotype 1 | 5 |
Genotype 2 | 2 | ||||
Genotype 3 | 9 | ||||
Undetermined | 31 | ||||
Wasmuth et al[33] | No | No | No | Genotype 1 | 213 |
Non-Genotype 1 | 117 | ||||
Woitas et al[11] | Yes | Not mentioned | Not mentioned | Genotype 1 | 95 |
Genotype 2 | 16 | ||||
Genotype 3 | 10 | ||||
Genotype 4 | 6 | ||||
Multiple genotype | 5 | ||||
Undetermined | 2 | ||||
Present study Goyal et al | No | No | No | Genotype 1 | 16 |
Genotype 2 | 1 | ||||
Genotype 3 | 161 | ||||
Genotype 4 | 4 | ||||
Undetermined | 70 |
- Citation: Goyal A, Suneetha P, Kumar G, Shukla DK, Arora N, Sarin SK. CCR5Δ32 mutation does not influence the susceptibility to HCV infection, severity of liver disease and response to therapy in patients with chronic hepatitis C. World J Gastroenterol 2006; 12(29): 4721-4726
- URL: https://www.wjgnet.com/1007-9327/full/v12/i29/4721.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i29.4721