Hepatectomy for huge hepatocellular carcinoma in 634 cases

Table 3 Univariate analysis on prognostic factors associated with long-term survival in patients with huge hepatocellular carcinoma undergoing liver resection

Variable		Patients(n)	Survival rates (%)
			1 yr	2 yr	3 yr	5 yr
Patients
Sex	Male	332	65.1	43.7	33.7	15.1	P < 0.05
	Female	24	83.3	70.8	45.8	37.5
Age	< 50 yr	206	64.5	42.7	32.0	15.1	NS
	≥ 50 yr	150	68.7	46.3	38.0	18.7
1AFP ng/mL	< 400	130	68.4	49.2	37.7	19.2	P < 0.05
	≥ 400 ng/mL	154	62.3	32.5	26.0	9.1
Tumor size
10-15 cm		281	71.5	46.6	39.5	17.4	P < 0.05
> 15 cm		75	46.7	41.3	16.0	0
Capsule
Positive		270	71.0	48.1	44.0	21.9	P < 0.05
Negative		86	48.8	37.2	4.7	0
Extensive capsular infiltration
Positive		224	67.4	40.6	39.3	12.1	P < 0.05
Negative		46	93.5	84.8	76.1	69.6
Tumor thrombus in portal vein
Positive		62	38.7	22.6	6.5	0	P < 0.05
Negative		294	72.1	50.3	40.5	20.1
Satellite nodules
Positive		87	36.8	23.0	12.6	0	P < 0.01
Negative		269	75.8	52.8	41.6	21.9
Surgical resection margin
≤ 10 mm		251	64.1	40.2	34.3	13.9	NS
> 10 mm		105	71.4	58.1	35.2	22.9
Intraoperative blood loss
≤ 800 mL		260	69.6	43.8	33.5	15.4	NS
> 800 mL		96	57.3	50.0	37.5	19.8

¹n = 498.