Anti-inflammatory effect of Diammonium Glycyrrhizinate in a rat model of ulcerative colitis

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Jul 28, 2006 (publication date) through Dec 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2006; 12(28): 4578-4581
Published online Jul 28, 2006. doi: 10.3748/wjg.v12.i28.4578

Table 4 Expression of TNF-a ,ICAM-1 and NF-kB p65 in injured colon

Group	TNF-α		ICAM-1		NF-κB p65
	Percentage	Density	Percentage	Density	Percentage	Density
DG	32.2 ± 8.2^b^d^f	37.3 ± 7.0^b^d^f	34.3 ± 8.2^b^d^f	36.1 ± 6.1^b^d^f	23.3 ± 5.2^b^d^f	31.2 ± 7.8^b^d^f
Dexamethasone 18.7 ± 5.7^b^d 18.5 ± 5.2^b^d 15.5 ± 4.3^b^d 17.6 ± 4.9^b^d	17.9 ± 5.6^b^d	19.0 ± 5.2^b^d	18.7 ± 5.7^b^d	18.5 ± 5.2^b^d	15.5 ± 4.3^b^d	17.6 ± 4.9^b^d
Acetic acid control ± 8.3^b 70.7 ± 9.7^b 44.5 ± 8.9^b 51.5 ± 9.8^b	52.5 ± 9.1^b	74.1 ± 9.5^b	60.2 ± 8.3^b	70.7 ± 9.7^b	44.5 ± 8.9^b	51.5 ± 9.8^b
Normal control 9.1 ± 4.4 9.4 ± 4.9 7.6 ± 4.1 8.1 ± 4.2	7.6 ± 5.7	9.0 ± 4.8	9.1 ± 4.4	9.4 ± 4.9	7.6 ± 4.1	8.1 ± 4.2

^bP < 0.01, vs Normal control group;

^dP < 0.01, vs Acetic acid control group;

^fP < 0.01, vs Dexamethasone group.

Citation: Yuan H, Ji WS, Wu KX, Jiao JX, Sun LH, Feng YT. Anti-inflammatory effect of Diammonium Glycyrrhizinate in a rat model of ulcerative colitis. World J Gastroenterol 2006; 12(28): 4578-4581
URL: https://www.wjgnet.com/1007-9327/full/v12/i28/4578.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i28.4578