Oncological problems in pancreatic cancer surgery

Table 1 Comparative studies of extended versus standard operation for pancreatic cancer

Author	Yr	Results
Ishikawa et al[24]	1988	Retrospective study	standard (n = 37): 9%, 5-Y-S
			extended (n = 22): 28%, 5-Y-S
Mukaiya et al[25]	1998	Retrospective study 77 institutions, 501 patients: NS
Henne-Bruns et al[26]	2000	Retrospective study	standard (n = 26)	NS
			extended (n = 46)
Pedrazzoli et al[27]	1998	RCT	standard (n = 40)	overall survival: NS
			extended (n = 41)	survival of node positive patients: extended > standard
Yeo et al[28]	2002	RCT	standard (n = 146)	mortality: NS, morbidity: extended > standard,
			extended (n = 148)	survival: NS

RCT: Randomized controlled test; NS: Not significant.