Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced β-cell damage by inhibiting NF-κB

Figure 1 Protection of islets from STZ-induced destruction by CCE. Pancreases were obtained from normal controls (A, E), from STZ-injected (B, F), and from CCE pretreated for 7 d with concentrations of 100 mg/kg per day (C, G) or 250 mg/kg (D, H) subsequently injected with STZ. Islets were labeled with insulin antibody and FITC-labeled anti-guinea pig IgG, and examined by fluorescence microscopy (E-H). The cellular morphologies of these same islets and of adjoining exocrine regions were counterstained with H-E (A-D). Bar = 50 μm.