Mechanism of T cell hyporesponsiveness to HBcAg is associated with regulatory T cells in chronic hepatitis B

Figure 4 Comparison of CD4⁺CD25^high T cell population between patients with hepatitis B and healthy subjects. The cells that express CD4, CD25^high and CTLA-4 were identified by flow cytometry. Representative dot plots of an ex vivo sample of a patient with CHB is shown (A), numbers shown in the dot plot indicates percentage of cells in the quadrant lesion. Percentage of CD4⁺CD25⁺ T cells was shown for patients with CHB and healthy subjects (B).