A functional variant in the CD209 promoter is associated with DQ2-negative celiac disease in the Spanish population

doi:10.3748/wjg.v12.i27.4397

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Jul 21, 2006 (publication date) through Dec 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2006; 12(27): 4397-4400
Published online Jul 21, 2006. doi: 10.3748/wjg.v12.i27.4397

Table 3 Genotypic CD209 frequencies in DQ2 (-) (n = 29) and DQ2 (+) (n = 357) celiac patients and controls (n = 419) from the Madrid area

Genotype	DQ2 (-) patients	DQ2 (+) patients	Controls
Genotype	n (%)	n (%)	n (%)
AA	18 (62)	207 (58)	255 (61)
AG	6 (21)	131 (37)	142 (34)
GG	5 (17)	19 (5)	22 (5)

3*2 contingency table DQ2- vs DQ2+: P = 0.017; 3*2 contingency table DQ2- vs controls: P = 0.019; carriers A vs GG DQ2 (-) vs DQ2 (+): P = 0.026 OR = 3.71 (1.10-11.78); carriers A vs GG DQ2 (-) vs controls: P = 0.023 OR= 3.76 (1.14-11.73).

Citation: Núñez C, Rueda B, Martínez A, Maluenda C, Polanco I, López-Nevot M, Ortega E, Sierra E, Concha EGL, Urcelay E, Martín J. A functional variant in the CD209 promoter is associated with DQ2-negative celiac disease in the Spanish population. World J Gastroenterol 2006; 12(27): 4397-4400
URL: https://www.wjgnet.com/1007-9327/full/v12/i27/4397.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i27.4397