Experimental study of osthole on treatment of hyperlipidemic and alcoholic fatty liver in animals

Table 5 Levels of TC, TG, FFA, SOD, MDA and GSH-PX in liver after treatment with osthole for 6 wk in high fat-induced fatty liver quails (n = 10)

Group	TC (mg/g wet tissue)	TG (mg/g wet tissue)	FFA (mg/g wet tissue)	SOD (U/mg prot)	MDA (nmol/mg prot)	GSH-PX (vigor units)
Control	2.26 ± 0.56	11.42 ± 4.37	499.14 ± 90.73	368.10 ± 21.60	10.93 ± 2.44	121.53 ± 20.88
Model	6.94 ± 3.25b	17.34 ± 5.90a	418.97 ± 181.75	314.24 ± 17.91b	11.37 ± 1.71	111.23 ± 29.85
Osthole 5 mg/kg	4.32 ± 0.69c	16.05 ± 4.74	508.62 ± 180.05	343.20 ± 33.71c	10.73 ± 2.30	130.00 ± 38.82
Osthole 10 mg/kg	4.05 ± 1.82c	13.48 ± 2.55	478.45 ± 134.74	344.16 ± 10.25d	10.86 ± 3.56	151.40 ± 41.34c
Osthole 20 mg/kg	3.66 ± 1.14d	12.97 ± 2.38c	419.83 ± 106.21	353.70 ± 33.95d	10.73 ± 0.95	174.35 ± 46.43d
Lipanthyl 20 mg/kg	4.05 ± 1.06c	14.87 ± 6.21	731.03 ± 237.13d	357.98 ± 16.08d	11.02 ± 1.90	150.05 ± 46.54c

^cP < 0.05,

^dP < 0.01 for medicine-treated animal versus model animal.