Experimental study of osthole on treatment of hyperlipidemic and alcoholic fatty liver in animals

Table 4 Serum levels of TC, TG, HDL-C, LDL-C, FFA and the relative hepatic weight after treatment with osthole for 6 wk in high fat-induced fatty liver quails (n = 10)

Group	TC (mmol/L)	TG (mmol/L)	HDL-C (mmol/L)	LDL-C (mmol/L)	FFA(μmol/L)	Relative hepatic weight (g/100 g)
Control	5.74 ± 0.51	0.68 ± 0.14	5.12 ± 0.48	0.31 ± 0.23	963.21 ± 231.70	1.89 ± 0.16
Model	9.53 ± 3.92b	0.89 ± 0.21a	5.35 ± 0.98	3.78 ± 3.36b	1303.77 ± 372.58a	2.13 ± 0.19b
Osthole 5 mg/kg	7.34 ± 0.88	0.49 ± 0.08d	5.50 ± 0.58	1.62 ± 0.73	938.68 ± 146.77d	1.83 ± 0.11d
Osthole 10 mg/kg	7.32 ± 1.53	0.57 ± 0.16d	5.56 ± 0.93	1.50 ± 1.41	794.34 ± 225.05d	1.83 ± 0.25d
Osthole 20 mg/kg	6.89 ± 0.84c	0.45 ± 0.05d	5.72 ± 0.75	0.98 ± 1.19c	783.96 ±1 04.05d	1.78 ± 0.13d
Lipanthyl 20 mg/kg	6.74 ± 0.73c	0.55 ± 0.10d	5.87 ± 0.66	0.62 ± 0.53d	1170.75 ± 425.34	1.76 ± 0.19d

^aP < 0.05,

^bP < 0.01 vs control animal.

^cP < 0.05,

^dP < 0.01 vs model animal.