Experimental study of osthole on treatment of hyperlipidemic and alcoholic fatty liver in animals

Table 2 Levels of TC, TG, SOD, MDA and GSH-PX in liver after treatment with osthole for 6 wk in alcohol-induced fatty liver rats (n = 10)

Group	TC (mg/g wet tissue)	TG (mg/g wet tissue)	SOD (U/mg prot)	MDA (nmol/mg prot)	GSH-PX (vigor units)
Control	1.94 ± 0.24	15.27 ± 3.35	58.33 ± 4.28	4.14 ± 1.34	174.86 ± 49.56
Model	2.25 ± 0.36a	18.88 ± 3.81a	50.04 ± 8.20a	5.36 ± 0.82a	206.80 ± 66.07
Osthole 5 mg/kg	1.82 ± 0.38d	16.19 ± 4.21	61.11 ± 3.26d	3.90 ± 1.35d	203.80 ± 41.24
Osthole 10 mg/kg	1.80 ± 0.25d	14.25 ± 3.10d	61.45 ± 3.62d	3.74 ± 0.99d	182.30 ± 31.42
Osthole 20 mg/kg	1.76 ± 0.21d	13.67 ± 4.30d	58.91 ± 3.72d	2.88 ± 0.92d	171.89 ± 32.44
Lipanthyl 20 mg/kg	1.61 ± 0.20d	12.84 ± 3.22d	53.80 ± 2.49	2.59 ± 0.54d	200.95 ± 55.26

^aP < 0.05, ^bP < 0.01 vs control animal. ^cP < 0.05,

^dP < 0.01 vs model animal.