Assessment of liver fibrosis by a noninvasive method of transient elastography and biochemical markers

Table 4 Comparison of diagnostic accuracy of FibroScan and other markers

Fibrotic Area >10%
	OC	Sens	Speci	SE	95% CI	AUC
FibroScan	9.1	100	76.9	0.047	0.777 - 0.999	0.932
HA	96.0	76.5	84.6	0.080	0.618 - 0.924	0.803
Col	6.6	52.9	100	0.081	0.615 - 0.923	0.801
APRI	0.57	76.5	84.6	0.081	0.615 - 0.923	0.801
Fibrotic Area > 20%
	OC	Sens	Speci	SE	95% CI	AUC
FibroScan	13.6	100	95.5	0.024	0.868 - 1.000	0.991
HA	106.0	100	77.3	0.061	0.797 - 0.993	0.946
Col	6.6	87.5	90.9	0.071	0.758 - 0.985	0.918
APRI	0.58	87.5	68.2	0.098	0.642 - 0.937	0.824

OC: Optimal cut off level; Sens: Sensitivity; Speci: Specificity; SE: Standard error; CI: Confidence interval; AUC: Area under the curve; HA: Hyaluronate; Col: Type IV collagen; APRI: AST-to platelet ratio index.