Antiviral treatment of hepatitis B virus-transgenic mice by a marine organism, Styela plicata

Figure 2 Representative examples of haematoxylin and eosin (HE) staining of HBV-Tg liver (× 400). The expression of infiltrating lymphocyte was strongly positive (white arrow) before drug administration. The structure of hepatic lobule was obscure and the swelling degree of liver cells was serious. Many vacuoles (black arrow) could be seen in (A). However, these findings were alleviated after 10 wk of therapy by Sp (B).