Correlative studies on uPA mRNA and uPAR mRNA expression with vascular endothelial growth factor, microvessel density, progression and survival time of patients with gastric cancer

Table 1 Correlation of uPA mRNA, uPAR mRNA and VEGF expression and clinicopathologic parameters in gastric cancer

Clinicopathologic parameters	n	uPA mRNA				uPAR mRNA				VEGF
		-	+	++	+++	-	+	++	+++	-	+	++	+++
Growth pattern
Expansive	48	29	8	3	8	21	8	8	11	24	6	8	10
Infiltrative	57	15	8	11	23b	14	7	17	19a	14	5	13	25a
Invasive depth
T1-T2	44	27	9	2	6	20	11	6	7	31	5	5	3
T3-T4	61	17	7	12	25b	15	4	19	23b	7	6	16	32b
Vessel invasion
Absent	29	16	8	2	3	14	8	2	5	25	3	1	0
Present	76	28	8	12	28b	21	7	23	25b	13	8	20	35b
Lymph node metastasis
Absent	35	21	8	3	3	17	8	2	8	27	5	1	2
Present	70	23	8	11	28	18	7	23	22	11	6	20	33b
Distant metastasis
Absent	63	39	16	1	7	29	14	8	12	36	10	10	7
Peritoneum metastasis	24	2	0	11	11b	2	0	11	11b	0	0	9	15b
Liver metastasis	18	3	0	2	13	4	1	6	7	2	1	2	13

^aP < 0.05, ^bP < 0.01.