Platelet-activating factor in liver injury: A relational scope

Table 1 Experimental studies of IR liver injury evaluating the role of PAF through its antagonism

Ischemia				Reperfusion
Type ofischemia	Splanchniccongestion	Duration	PAF-Rantagonist	Type ofreperfusion	Duration	Reference
is, T, W	No	120 min	TCV-309	is	1, 3, 6 h - s 7 d	[34]
is, T, W	No	120 min	TCV-309	is	30 min, 1, 3, 6 h - s 30 d	[33]
is, T, W	No	120 min	TCV-309	is	60 min - s 30 d	[32]
is, T, W	Yes	20 min	E5880	is	30 min	[31]
is, T, W	Yes	45 min	BB-882 (lexipafant)	is	45 min	[35]
is, T, W	NA	120 min	WEB-2170	is	6, 24 h	[37]
is, T, W	NA	60 min	BN-52021	is	60 min	[38]
is, P, W	No	60 min	WEB-2170	is	1, 3, 6, 24 h	[24]
is, P, W	No	30, 45 min	WEB-2170	is	1 h	[28]
is, P, W	No	60 min	BN-52021	is	30 min	[27]
is, P, W	No	60 min	BN-52021	is	30 min	[29]
is, P, W	No	75 min	BN-52021	is	24 h - s 7 d	[26]
is, P, W	No	30, 60, 90 min	CV-6209	is	15, 30, 60, 120 min	[23]
Is, T, W+C	NA	90 min (W), 24 h (C)	CV-6209	Is	60 min (W), 120 min (C)	[19]
is, T, W	NA	90 min	SRI-63441	Is	90 min	[20]
Is, T, C	NA	24 h	SRI-63441	Is	90 min	[18]

is: In situ; Is: Isolated; T: Total; P: Partial; W: Warm; C: Cold; NA: Not applicable; s: Survival; d: Days.