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Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Jun 14, 2006; 12(22): 3537-3545
Published online Jun 14, 2006. doi: 10.3748/wjg.v12.i22.3537
Figure 1
Figure 1 Additive effect of estrogens (EE) and insulin like growth factor-1 (IGF1) in the modulation of cholangiocyte proliferation. EE and IGF1 play additive effects on cholangiocyte proliferation by acting at both receptor and post-receptor levels IGF1 and EE induce, in cholangiocytes, additive increase of phosphorylated ERK1/2.