Apoptosis of human colon carcinoma HT-29 cells induced by ceramide

Table 3 C₂-ceramide damaged mitochondria function of HT-29 cells (mean ± SD)

C2-ceramide (mmol/L)	1 h	3 h	6 h	9 h	12 h	24 h
0	0.505 ± 0.061	0.596 ± 0.050	0.528 ± 0.083	1.088 ± 0.134	1.371 ± 0.066	1.770 ± 0.161
12.5	0.478 ± 0.044	0.609 ± 0.048	0.502 ± 0.029	0.833 ± 0.149a	1.036 ± 0.122	1.560 ± 0.220
25	0.487 ± 0.051	0.568 ± 0.048	0.404 ± 0.033a	0.646 ± 0.158a	0.760 ± 0.086a	1.484 ± 0.346a
50	0.490 ± 0.054	0.541 ± 0.049	0.345 ± 0.050a	0.456 ± 0.071a	0.708 ± 0.073a	1.342 ± 0.061a

^aP < 0.05 vs control.