Adiponectin deficiency exacerbates lipopolysaccharide/D-galactosamine-induced liver injury in mice

Figure 4 The expressions of adipoR1 and AdipoR2 in Kupffer cells (A). Effect of adiponectin on TNF-α, IL-10 and IFN-γ production by LPS-stimulated Kupffer cells in vitro (B-D). Pre-treated with or without adiponectin (10 mg/L) for 24 h followed by the stimulation with LPS (10 mg/L). TNF-α, IL-10 and IFN-γ mRNA expression in Kupffer cells after LPS stimulation (E-G). (mean ± SE, n = 6). ^aP < 0.05, ^bP < 0.01 (Scheffé’s test).