Matrix-derived serum markers in monitoring liver fibrosis in children with chronic hepatitis B treated with interferon alpha

Table 1 Baseline characteristics of the group of children with chronic hepatitis B

Data of the patients	Mean	SD	Minimum	Maximum
Age (yr)	8	3.51	4	16
HBV infection (mo)	44	30	10	144
ALT (nkat/L)	1600	1567	350	9902
AST (nkat/L)	1367	1117	567	7718
GGT (nkat/L)	250	150	50	1150
Bilirubin (μmol/L)	8.5	4.3	3.4	23.9
Albumin (g/L)	65.6	4.2	57.2	74.3
Hyaluronan (μg/L)	34.3	21.5	14.6	113.5
Tenascin (μg/L)	748.8	265.9	295.6	1480.2
TIMP-1(μg/L)	558.1	121.2	342.2	852.3
Collagen VI (μg/L)	5.8	2.2	2.3	14.2
Staging	2.0	0.6	1	3
Grading	1.6	0.7	1	3

Normal ranges: AST: 167-667 nkat/L; ALT: 167-667 nkat/L; GGT: 150-583 nkat/L; Bilirubin: 1.7-18.8 μmol/L; Albumin: 58.8-69.6 g/L.