Relationships between mucinous gastric carcinoma, MUC2 expression and survival

Table 1 MUC expression in 31 gastric carcinomas stratified according to Laurén’s classification, Mulligan’s classification, WHO classification and Goseki’s classification n (%)

Parameter	n	MUC2		MUC5AC		MUC5B		MUC6
		+ IHC1	+ ISH	+ IHC	+ ISH	+ IHC	+ ISH	+ IHC	+ ISH
Laurén
Intestinal	14	3 (21)	13 (93)	8 (57)	7 (50)	12 (86)	5 (36)	6 (43)	6 (43)
Diffuse	12	1 (8)	6 (50)a	9 (75)	8 (67)	9 (75)	3 (25)	5 (42)	3 (25)
Unclassified	5	3 (60)	4 (80)	3 (60)	1 (20)	3 (60)	1 (20)	1 (20)	2 (40)
Mulligan
Intestinal cell	18	5 (28)	16 (89)	11 (61)	8 (44)	15 (83)	6 (33)	7 (39)	7 (39)
Mucous cell	13	2 (15)	7 (54)	9 (69)	8 (62)	9 (69)	3 (23)	5 (38)	4 (31)
Pylorocardiac	0	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
WHO
Papillary	0	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
Tubular	14	3 (21)	13 (93)	8 (57)	7 (50)	12 (86)	5 (36)	6 (43)	6 (43)
Mucinous	3	3 (100)a	3 (100)	2 (67)	0 (0)	2 (67)	0 (0)	0 (0)	1 (33)
Signet-ring cell	12	1 (8)	6 (50)a	9 (75)	8 (67)	9 (75)	3 (25)	5 (42)	3 (25)
Undifferentiated	2	0 (0)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)	1 (50)
Goseki
Group I	11	2 (18)	10 (91)	5 (45)	4 (36)	9 (82)	2 (18)	5 (45)	4 (36)
Group II	5	4 (80)b	5 (100)	4 (80)	2 (40)	4 (80)	2 (40)	1 (20)	2 (40)
Group III	9	0 (0)	4 (44)	6 (67)	5 (56)	5 (56)	3 (33)	3 (33)	4 (44)
Group IV	6	1 (17)	4 (67)	5 (83)	5 (83)	6 (100)	2 (33)	3 (50)	1 (17)

¹ MUC2 positivity in more than 30% of tumoral cells. IHC: Immu-nohistochemistry; ISH: In situ hybridization.

^aP < 0.05,

^bP = 0.01 vs other groups.