Ameliorative effect of Ganoderma lucidum on carbon tetrachloride-induced liver fibrosis in rats

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Jan 14, 2006 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2006; 12(2): 265-270
Published online Jan 14, 2006. doi: 10.3748/wjg.v12.i2.265

Table 5 Effect of GLE on hepatic protein, malondialdehyde and hydroxyproline content in CCl₄-treated rats

Group	Dose (mg/kg)	Protein(mg/g tissue)	Malondialdehyde(nmol/mg protein)	Hydroxyproline(µg/g tissue)
Control	-	186.3 ± 26.4	2.6 ± 0.5	550.0 ± 42.5
CCl₄ + H₂O	-	108.7 ± 4.8 ^d	4.4 ± 1.1^d	1201.2 ± 151.7^d
CCl₄ + GLE	600	124.4 ± 10.2	3.8 ± 0.4	1050.4 ± 187.2^b
	1600	128.2 ± 13.5^a	3.4 ± 0.5^a	877.5 ± 137.9^b

^aP < 0.05, ^bP < 0.01 vs CCl₄ + H₂O group; ^dP < 0.001 vs control group.

Citation: Lin WC, Lin WL. Ameliorative effect of Ganoderma lucidum on carbon tetrachloride-induced liver fibrosis in rats. World J Gastroenterol 2006; 12(2): 265-270
URL: https://www.wjgnet.com/1007-9327/full/v12/i2/265.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i2.265