Effect of hepatic iron concentration reduction on hepatic fibrosis and damage in rats with cholestatic liver disease

Table 1 Weights and phlebotomy volume in different groups of rats (mean±SE)

Subgroup	n	Weight gain(% from baseline)	Mean phlebotomy Volume1(mL)	Liver weight(% of total body weight)	Splenic weight(% of total body weight)
Sham only	5	15.03  ±  18.70a	0  ±  0	3.97  ±  0.16a	0.41 ± 0.07a
Sham and phlebotomy later	4	9.4  ±  7.0	0.70  ±  0.13	3.62  ±  0.32	0.37 ± 0.04
Phlebotomy and sham later	6	-5.7 ± 17.3	0.86  ±  0.18	3.47  ±  0.19	0.38 ± 0.03
BDL only	9	-4.99  ±  3.90	0  ±  0	6.89  ±  1.29	0.66 ± 0.10
BDL and phlebotomy later	8	8.01  ±  3.1a	0.71  ±  0.16	5.97  ±  0.45	0.56 ± 0.07
Phlebotomy and BDL later	8	-3.29  ±  20.1	0.80  ±  0.15	7.02  ±  1.68	0.69 ±0.13

¹Mean phlebotomy volume for one phlebotomy session per rat;

^aP ≤ 0.01 vs BDL only.