Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins

Figure 7 Changes in the intracellular concentration of Ca²⁺ in response to capsaicin and lafutidine in HEK293 cells transfected with VR1. Rat VR1 was introduced into HEK293 cells. Capsaicin (10^-8-10^-6 mol/L) or lafutidine (10^-4 mol/L) was added to the medium. Data are presented as the mean ± SE from 3 experiments. ^aP < 0.05 vs control.