Selective inhibition of cell growth by activin in SNU-16 cells

Figure 3 Effects of activin A on activin receptor mRNA expression (A), smad mRNA expression (B), and p21^CIP1/WAF1 mRNA expression (C) in SNU-16 cells. Cells (5 × 10⁴ cells/mL) were cultured with activin A (100 ng/mL) in a time-dependent manner and mRNA levels were measured by RT-PCR. Values are mean ± SD of three individual experiments and reported as the ratio of activin receptors to β-actin signals, the ratio of Smad to β-actin signals, and the ratio of p21^CIP1/WAF1 to β-actin signals, respectively. ^aP < 0.05 and ^bP < 0.01 vs the control values.