Optimal injection volume of epinephrine for endoscopic treatment of peptic ulcer bleeding

Table 3 Changes in systolic blood pressure and pulse before and after endoscopic injection therapy (n = 76, mean±SD)

	Epinephrine(20 mL) n (%)	Epinephrine(30 mL) n (%)	Epinephrine(40 mL) n (%)
Pressure (mmHg)
Before treatment	108.2 ± 31.8	109.3 ± 29.3	106.2 ± 30.7b
After treatment	110.3 ± 21.9	112.7 ± 22.5	129.3 ± 25.8b
Pulse (/min)
Before treatment	96.5 ± 14.7d	98.2 ± 15.3d	96.7 ± 14.3
After treatment	84.8 ± 12.8d	86.3 ± 12.5d	101.4 ± 15.2

^bP < 0.01 (paired t-test) in the 40 mL epinephrine group;

^dP < 0.01 (paired t-test) in the 20 mL and 30 mL epinephrine groups.