Wnt/β-catenin signaling pathway is active in pancreatic development of rat embryo

Figure 2 (A-D) Representative immunohistochemical results of β-catenin, APC and cyclin D1 proteins in embryonic pancreas of E14. 5-E18.5 and adult rat. Immunohistochemical staining was performed using an anti-β-catenin APC and cyclin D1antibodies respectively. Slides were detected at ×400 magnification under a light microscope. A: showed staining of β-catenin at cytoplasm (black arrow) and nucleus (red row) in embryonic pancreas of E18.5. B: showed staining of cyclin D1 within cytoplasm (black arrow) and/or nucleus (red row) in embryonic pancreas of E16.5. C: showed staining of APC within cytoplasm (black arrow) in embryonic pancreas of E18.5. D: showed staining of APC within cytoplasm (black arrow) in adult rat pancreas.