Antibody to E1 peptide of hepatitis C virus genotype 4 inhibits virus binding and entry to HepG2 cells in vitro

Figure 1 Sequence alignment of amino acids no 311 to 370 ( numbering starts from initiating methionin in the core protein of genotype 4a) of HCV E1 among representative genotypes. Eight sequences of different subtypes were aligned using ClustalW software, the output diagram is shown with the legend on the left having the accession number and the subtypes. Sequences shown in bold represent the highly conserved amino acid stretch (GHRMAWDMM) used for production of polyclonal antibody.