Filtrate of fermented mycelia from Antrodia camphorata reduces liver fibrosis induced by carbon tetrachloride in rats

Table 3 Effect of FMAC on spleen weight, hepatic malondialdehyde and hydroxyproline contents in CCl₄-treated rats

Group	Dose	Spleen	Malondialdehyde	Hydroxyproline
	(g/kg per d)	(g)	(μmol/g protein)	(μg/g tissue)
Control	–	1.1 ± 0.1	1.9 ± 0.1	645.0 ± 64.5
CCl4 + H2O	–	2.7 ± 0.1d	3.9 ± 0.1d	1730.7 ± 258.0d
CCl4 + FMAC	0.5	2.8 ± 0.2	2.7 ± 0.1	1741.5 ± 257.1
	1	2.4 ± 0.2a	2.4 ± 0.6b	1311.5 ± 238.8b

^aP < 0.05, ^bP < 0.01 vs CCl₄ + H₂O group; ^dP < 0.001 vs control group.