Molecularly defined adult-type hypolactasia in school-aged children with a previous history of cow’s milk allergy

Table 2 Milk consumption and abdominal symptoms in school-aged children genotyped for adult-type hypolactasia

	T/T1-13910	C/T1-13910	C/C2-13910
Total number of children
n = 172	n = 68	n = 77	n = 27
Milk products consumed	95%	95%	93%
(n = 163)	(54/62)	(67/74)	(25/27)
Drinks milk < 1 dL/day	22%	18%	44%a
(n = 146)	(12/54)	(12/67)	(11/25)
Low lactose content in the diet	7%	4%	36%b
(n = 146)	(4/54)	(3/67)	(9/25)
Skin prick test >3 mm to cow’s milk	13%5	11%5	12%3
(n = 168)	(9/67)	(8/75)	(3/26)

¹lactase persistence;

²defines adult-type hypolactasia;

^aP < 0.02 vs genotypes associated with lactase persistence (T/T-₁₃₉₁₀ plus C/T-₁₃₉₁₀);

^bP < 0.002 vs T/T-₁₃₉₁₀ genotype or C/T-₁₃₉₁₀ genotype;

³each of these prick positive children had a diagnosis of cow’s milk allergy at a mean age of seven mo[17].