Mechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas

doi:10.3748/wjg.v12.i14.2168

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Apr 14, 2006 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Gastric Cancer

World J Gastroenterol. Apr 14, 2006; 12(14): 2168-2173
Published online Apr 14, 2006. doi: 10.3748/wjg.v12.i14.2168

Table 1 Fraction of allelic loss (FAL) in tumors with different hypermethylation statuse

Promoterhypermethylation	FAL
Yes(++,+++)	0.098
Yes(+)	0.214
No	0.377	P = 0.03

FAL was estimated by allelic status at D16S3043, D16SS3050 and D16S3021. FAL (fraction of allelic loss) = number of loci showing LOH / number of informative loci in each tumor. The FALs of tumors with different hypermethylation status were calculated as the mean of FALs of individual tumors with the same hypermethylation status.

Citation: Liu YC, Shen CY, Wu HS, Hsieh TY, Chan DC, Chen CJ, Yu JC, Yu CP, Harn HJ, Chen PJ, Hsieh CB, Chen TW, Hsu HM. Mechanisms inactivating the gene for E-cadherin in sporadic gastric carcinomas. World J Gastroenterol 2006; 12(14): 2168-2173
URL: https://www.wjgnet.com/1007-9327/full/v12/i14/2168.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i14.2168