Adeno-associated virus-mediated heme oxygenase-1 gene transfer suppresses the progression of micronodular cirrhosis in rats

Figure 3 A and B: The liver function of rats with or with treatment under long-term CCl₄ toxicity was presented by the determination of plasma ALT and total bilirubin level. The data was shown as mean±SEM, n = 5-10, ^aP<0.001; C and D: The representative picture of the expression patterns of apoptotic genes in the livers at the 10^th week. The mRNA level of genes was detected by RNase protection assay. The quantification of the expression level was measured by phosphoimager as described in Materials & Methods. The data were shown as mean ± SE, n = 3-5, ^bP<0.05; E: The ATP level of the livers of rats with or without treatments at the 10^th wk, n  =  5-10, ^dP<0.001.