S-adenosyl-methionine decreases ethanol-induced apoptosis in primary hepatocyte cultures by a c-Jun N-terminal kinase activity-independent mechanism

Figure 8 Preventive effect of SP600125 and AdoMet on Bid cleavage, a component of the JNK signaling pathway. A: Western blot; B: densitometric analysis. The data represent mean± SE for n = 3. ^a indicates a significant difference in Bid fragmentation between SP600125- or Z-IETD-fmk-pretreated cells and cells exposed to ethanol only (P  <  0.05).