Interleukin-2 gene-encoded stromal cells inhibit the growth of metastatic cholangiocarcinomas

doi:10.3748/wjg.v12.i12.1889

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Mar 28, 2006 (publication date) through Nov 8, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2006; 12(12): 1889-1894
Published online Mar 28, 2006. doi: 10.3748/wjg.v12.i12.1889

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Figure 4 Gross findings of metastatic lung lesions in Syrian hamsters 8 wk after injection of KIGB-5 tumor cells in RPMI control (A), BMSCs (2. 5 x 10⁶ cells/d) (B), BMSCs containing 50 MOI Ad/∆E1 (2.5 x 10⁶ cells/day) (C), and BMSCs containing 50 MOI Ad/hIL-2 (2.5 x 10⁶ cells/d) (D). Hamsters injected with RPMI, BMSCs, or BMSCs containing Ad/∆E1 showed multiple metastatic lung lesions 8 wk after tumor injection, whereas hamsters injected with BMSCs containing Ad/IL-2 showed no evidence of disease.

Citation: Kim MH, Lee SS, Lee SK, Lee SG, Suh CW, Gong GY, Park JS, Kim YH, Kim SH. Interleukin-2 gene-encoded stromal cells inhibit the growth of metastatic cholangiocarcinomas. World J Gastroenterol 2006; 12(12): 1889-1894
URL: https://www.wjgnet.com/1007-9327/full/v12/i12/1889.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i12.1889