Expression of cytokeratins in Helicobacter pylori –associated chronic gastritis of adult patients infected with cagA+ strains: An immunohistochemical study

Figure 5 CK7 immunoreactivity in antral mucosa of patients with cagA+ H pylori chronic gastritis (A), non-H pylori chronic gastritis (B), control subjects with normal gastric mucosa (C), and control specimen of human fetal esophagus (D). Moderate focal CK7 positivity (→) in the pits and the glands of antral mucosa in patients with cagA+ H pylori chronic gastritis could be observed. CK7 positive cells covering a single gland (→) of antral mucosa could be found in patients with non-H pylori chronic gastritis. Normal antral mucosa with a few single cells or cell clusters (→) were strongly decorated with antibody to CK7. Strong CK7 immunoreactivity was displayed in the stratified columnar epithelium (→) of human fetal esophagus of the 13^th gestation week. Original magnification: x10 (A-D).