Expression of cytokeratins in Helicobacter pylori –associated chronic gastritis of adult patients infected with cagA+ strains: An immunohistochemical study

Table 6 Expression of CK7 in antral mucosa of patients with gastritis (H pylori positive and negative) compared to the control group

Cytokeratin 7expression	Antral mucosa epithelium
	H pylori+G		H pylori-G		CG		P
	n	%	n	%	n	%
Surface and foveolar epithelium
Weak focal
immunoreactivity	0	0	0	0	0	0	NS
Moderate focal
immunoreactivity	5	9.1	0	0	0	0	NS
<10% cells	0	0	0	0	0	0
10-20% cells	3	5.5	0	0	0	0
>20% cells	2	3.6	0	0	0	0
Without staining	50	90.9	16	100	10	100	NS
n (%)	55	100	16	100	10	100
Glandular necks and deep glands
Weak focal
immunoreactivity	6	10.9	1	6.3	3	30.0
<10% cells	3	5.5	1	6.3	3	30.0	0.01
10-20% cells	2	3.6	0	0	0	0	NS
>20% cells	1	1.8	0	0	0	0	NS
Moderate focal
immunoreactivity	38	69.1	10	62.5	7	70.0
<10% cells	10	18.3	10	62.5	7	70.0	0.002
10-20% cells	14	25.4	0	0	0	0	0.002
>20% cells	14	25.4	0	0	0	0	0.002
Without staining	11	20.0	5	31.2	0	0
n (%)	55	100	16	100	10	100

CG: control group; H pylori+G: Helicobacter pylori positive patients with gastritis; H pylori-G: Helicobacter pylori negative patients with gastritis; NS: P > 0.05.