Expression of cytokeratins in Helicobacter pylori –associated chronic gastritis of adult patients infected with cagA+ strains: An immunohistochemical study

Table 4 Expression of CK19 in antral mucosa of patients with gastritis (H pylori positive and negative) compared to the control group

Cytokeratin 19expression	Antral mucosa epithelium
	H pylori+G		H pylori-G		CG		P
	n	%	n	%	n	%
Surface epithelium
Expression in all cells	34	60.6	12	70.6	5	55.6	NS
Patchy staining	21	37.4	5	29.4	4	44.4
Without staining	1	2.0	0	0	0	0
n (%)	56	100	17	100	9	100
Foveolar epithelium
Expression in all cells	39	69.7	9	53.0	5	55.6	NS
Patchy staining	7	12.5	5	29.4	4	44.4	0.027
Moderate/Strong	2	3.6	2	11.8	2	22.2
Weak	5	8.9	3	17.6	2	22.2
Without staining	10	17.8	3	17.6	0	0	NS
n (%)	56	100	17	100	9	100
Glandular neck
Expression in all cells	37	58.1	9	53	6	66.7	NS
Patchy staining	10	17.8	6	25.2	3	33.3
Without staining	9	16.1	2	11.8	0	0
n (%)	56	100	17	100	9	100
Deep gland
Expression in all cells	22	39.2	6	35.2	3	33.3	NS
Patchy staining	10	17.8	5	29.5	2	22.2
Without staining	24	43.0	6	35.3	4	44.5
n (%)	56	100	17	100	9	100

CG: control group; H pylori+G: Helicobacter pylori positive patients with gastritis; H pylori-G: Helicobacter pylori negative patients with gastritis; NS: P > 0.05.