Effects of betaine on ethanol-stimulated secretion of IGF-I and IGFBP-1 in rat primary hepatocytes: Involvement of p42/44 MAPK activation

doi:10.3748/wjg.v12.i11.1718

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Mar 21, 2006 (publication date) through Dec 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 21, 2006; 12(11): 1718-1722
Published online Mar 21, 2006. doi: 10.3748/wjg.v12.i11.1718

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Figure 4 Betaine stimulates the phosphorylation of p42/44 MAPK in primary rat hepatocytes. A: Time-dependent activation of p42/44 MAPK by 10^-3 mol/L betaine, B: Dose-dependent activation of p42/44 MAPK by betaine for 300 min (left panel). Treatment with betaine following pretreatment with PD98059 for 10 min (right panel), C: Betaine-stimulated recovery of p42/44 MAPK activation in ethanol-treated cells.

Citation: Lee MS, Kim MS, Park SY, Kang CW. Effects of betaine on ethanol-stimulated secretion of IGF-I and IGFBP-1 in rat primary hepatocytes: Involvement of p42/44 MAPK activation. World J Gastroenterol 2006; 12(11): 1718-1722
URL: https://www.wjgnet.com/1007-9327/full/v12/i11/1718.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i11.1718