Assessment of metastatic liver disease in patients with primary extrahepatic tumors by contrast-enhanced sonography versus CT and MRI

Figure 3 Detection of multiple metastatic lesions in the liver of a patient with sarcoma. A: In contrast-enhanced sonography, the lesions show a periperal enhancement in the arterial phase (“rim sign”), indicating the arterial blood supply to the peripheral proliferation zone of this metastatic lesions from a hypervascular tumor. B: During portal-venous phase, the lesions show lack of portal-venous enhancement (‘black spot’), indication the absence of portal-venous blood flow typical for malignant liver lesions.