Protocol liver biopsies in long-term management of patients transplanted for hepatitis B-related liver disease

Table 2 Histological features in anti-HCV negative patients, transplanted for HBV-related liver cirrhosis with no HBV recurrence

	6	1	2	3	4	5	6	7	8
	mo	yr	yr	yr	yr	yr	yr	yr	yr
n	28	26	19	16	12	11	8	8	4
No. of biopsies/total biopsies (%)
Negative	5/26	9/23	4/19	6/14	6/12	3/10	4/8	4/8	1/2
	(19.2%)	(39.1%)	(21.0%)	(42.8%)	(50.0%)	(30.0%)	(50.0%)	(50.0%)	(50.0%)
Minimal, not	19/26	8/23	11/19	6/14	5/12	6/10	2/83/81/2
otherwise specified	(73.0%)	(39.7%)	(57.8%)	(42.8%)	(41.6%)	(60.0%)	(25.0%)	(37.5%)	(50.0%)
hanges
Mild chronic hepatitis	2/26	6/23	4/19	2/14	-	-	1/8
	(7.6%)	(26.0%)	(21.0%)	(14.2%)	-	-	(12.5%)
Moderate chronic	-	-	-	-	1/12	1/10	1/8	1/8
hepatitis					(8.3%)	(10.0%)	(12.5%)	(12.5%)
Severe chronic	-	-	-	-	-	-	-	-	-
hepatitis
Cirrhosis	-	-	-	-	-	-	-	-

Histological features in 122 liver biopsies performed in 28 anti-HCV negative patients transplanted for HBV-related liver disease with no HBV recurrence. The number of patients considered declined year by year and the total number of liver biopsies performed each year is less than the number of patients per year.