Association of the HLA-DRB1*0701 allele with perinuclear anti-neutrophil cytoplasmatic antibodies in Mexican patients with severe ulcerative colitis

Table 2 Clinical features of UC patients with positive and negative p-ANCA

Clinical	p-ANCA	p-ANCA	P value
feature	+	-
	n=48	n=42
Age at diagnosis (yr)	31 ± 8	33 ± 7	0.34
Gender (F/M)	23/25	22/20	0.62
Disease duration (yr)	7.4 ± 6.3	6.8 ± 6.2	0.45
Clinical relapses	2 ± 1	3 ± 2	0.25
Medical Treatment
5-ASA	90%	85%	0.75
Corticosteroids	44%	45%	0.90
Azatioprine or 6-MP	24%	22%	0.82
Extensive colitis	29	27	0.47
Distal colitis	19	15
Colectomy	7	7	0.94
No Colectomy	41	35
EIMs present	21	25	0.67
EIMs absent	27	17
Disease activity
Absent	19	21	0.82
Mild	9	10	0.71
Moderate	5	6	0.65
Severe	15	5	0.000008

^aOR = 11; CI 95%:4.0-34.0.n = Number of patients.