Risk factors for immediate post-operative fatal recurrence after curative resection of hepatocellular carcinoma

Table 4 Predictive values of risk factors for fatal recurrence after curative resection of HCC

	n	Number of fatalrecurrence1	PPV(%)	NPV(%)	Test efficiency (%)	P2
All three risk factors present	27	13	48.1	92.9	88.5	0.023
Only two risk factors present	50	11	22.0	91.3	78.4	0.023
Microvascular invasion and tumor size ≥ 6.5 cm	26	6	23.1	90.1	83.6	0.027
Microvascular invasion and AFP ≥ 1 000 ng/mL	21	4	19.0	89.5	84.0	0.027
Tumor size ≥ 6.5 cm and AFP ≥ 1 000 ng/mL	3	1	33.3	89.1	88.5	0.027
Only one risk factor present	71	5	7.0	87.4	66.2	0.027
Micro-vascular invasion	33	3	9.1	88.6	78.8	0.027
Tumor size ≥ 6.5 cm	15	1	6.7	88.6	84.0	0.027
AFP ≥ 1 000 μg/L	23	1	4.3	88.2	81.1	0.027
No risk factor present	121	1	0.8	80.4	44.6	0.027
Number of total patients	269	30				0.027

PPV: positive predictive value; NPV: negative predictive value;

¹Number of patients with fatal recurrence within 6 mo of surgery; ²Statistical difference of PPV between patients with fatal recurrence within 6 months of surgery according to number of risk factors in each group.