Effects of emodin on treating murine nonalcoholic fatty liver induced by high caloric laboratory chaw

Figure 4 Hepatopathological manifestations among four groups. A: Murine normal liver tissue stained with HE. A1: HE×100, A2: HE×400; B: Demonstration of fatty liver tissues in model control group. Moderate to severe macro vesicular steatosis, diffusely distributed throughout the liver lobule, and parenchymal inflammation with both acute and chronic inflammatory cells accompanying focal necrosis. B1: HE×100, B2: HE×400; C: Significant improvement of liver steatosis in emodin group. There was significant reduction of fatty deposits in liver tissues and the histologic figures restored to nearly normal. C1: HE×100, C2: HE×400; D: Liver steatosis in dietary group. The degree of liver steatosis was improved, but mild steatosis still existed. D1: HE×100, D2: HE×400.