Basic Research
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Mar 7, 2005; 11(9): 1303-1316
Published online Mar 7, 2005. doi: 10.3748/wjg.v11.i9.1303
Table 2 Summary of Northern blot expression data of rat liver lobes after partial WI/R (1h/2h).
DescriptionUp-regulated genes (C-lobes vs I-lobes; n = 14)
UniGene IDAccession number% Identity1MethodMean fold increase2SE3WI/R citation4
Stress response
Heat shock 10 ku protein 1 (Hspe1,Hsp10)Rn.106093NM_012966idSSH2.8 (n = 4)1.4
Heat shock protein 27 ku (Hsp27)Rn.3841M86389idA13.7 (n = 4)1.6[21, 27]
Heat shock protein 60 ku (liver) (Hsp60)Rn.102058X54793idA1.4 (n = 4)1.4
Heat shock 70 ku protein 1A (Hspa1a,Hsp70)Rn.1950L16764idSSH/A64.0 (n = 4)1.6[22, 36-39]
Heat shock 70 ku protein 8 (Hspa8, Hsc70)Rn.120392M11942idSSH1.5 (n = 4)1.5[37, 40]
Heat shock protein 1, alpha (Hspca,Hsp86)Rn.3277AJ297736idSSH2.5 (n = 4)1.1[39]
Similar to heat shock protein 105 ku alpha (LOC288444, Hsp105)Rn.37805XM_213699idSSH1.9 (n = 4)1.1
Cell cycle arrest, DNA damage, apoptosis
Growth and DNA-damage-inducible transcript-1 (Gadd45a)Rn.10250L32591idA3.7 (n = 4)1.2
Transcription factor
Jun D proto-oncogene (Jund)Rn.46225NM_138875idA4.6 (n = 4)1.3[9, 29]
c-fos mRNA (Fos)Rn.103750XM_234422idA16.3 (n = 4)1.9[9, 28, 29, 36, 37, 41]
Avian sarcoma virus 17 oncogene homolog (Jun)Rn.93714NM_021835idA2.5 (n = 3)1.5[9, 28, 29, 36, 41]
Cellular metabolism
Low density lipoprotein receptor (Ldlr)Rn.10483X13722idA9.1 (n = 4)1.4
Gene product function unknown
ESTsRn.16092BM391881idSSH5.2 (n = 4)1.2
ESTsRn.2835BG664888idSSH3.6 (n = 4)1.4