Up-regulation of intestinal nuclear factor kappa B and intercellular adhesion molecule-1 following traumatic brain injury in rats

Figure 4 ICAM-1 immunohistochemical staining of jejunal tissue, indicated by the arrows. A: almost undetectable ICAM-1 expression in the villi from control rats; B: moderate ICAM-1 immunoreactivity in the villous interstitium at 24 h postinjury, with the villi well defined; C: strong ICAM-1 immunoreactivity in the villous interstitium at 72 h postinjury, with the villi disarranged and the ICAM-1 positive endothelial cells shown as nigger-brown granules; D: marked ICAM-1 immunohistochemical staining of microvessels in the intestinal lamina propria at 72 h postinjury; E: high ICAM-1 immunoreactivity in the villous interstitium at 7 d postinjury, with the villi atrophic and sparse.